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Faculty: Elaine Eisenbeisz


  • Date:10/14/2021 01:00 PM - 10/14/2021 02:30 PM
  • Time zone: Eastern Time (US/Canada) Online Event

Description

Attendees of this webinar will learn statistically valid methods for using small sample sizes and for using lots as few as 3 when validating processes or products.

The focus of this webinar is on providing the information needed for attendees to understand the concepts of risk in relation to process validation and to be able to compute sample sizes and lot sizes according the desired or required specification criteria or the process or product.

Why You Should Attend:

Regulatory and certification bodies have requirements for the validation of processes. 21 CFR Part 820.75 (a) Process validation states,” Where the results of a process cannot be fully verified by subsequent inspection and test, the process shall be validated with a high degree of assurance and approved according to established procedures.” Additionally, ISO 9001:2008 7.5.2 Validation of processes for production and service provision states “The organization shall validate any processes for production and service provision where the resulting output cannot be verified by subsequent monitoring or measurement and, as a consequence, deficiencies become apparent only after the product is in use or the service has been delivered.”

Attend this webinar to understand the concepts of risk about process validation and learn to compute sample sizes and lot sizes according to the desired or required specification criteria or the process or product. 100% testing in most manufacturing processes would require 100% destruction of the product being made. Therefore it is important to know the minimum amount of product to sample from a minimum number of lots in order to preserve inventory while minimizing risk (such as loss of product, consumer risk of defectives, etc.)

Learning Objectives:

  • Knowledge of the regulatory requirements of process validation
  • Terminology and concepts of process validation
  • How to calculate the sample size
  • How to calculate number of lots needed.

Areas Covered in the Session :

  • Regulatory Requirements
  • Concepts and Terminology
  • Calculation of sample size to be taken from each lot in a validation study
  • Calculation of confidence and reliability measurement for production process
  • Calculation of confidence and reliability measurement for each lot
  • A worked example will be presented.
  • Example of a summary “justification statement”

Who Should Attend:

  • QA/QC Supervisors
  • Process Engineers
  • Manufacturing Engineers
  • QA/QC Technicians
  • Manufacturing Technicians
  • R&D Engineers